![]() capable of causing disease in humans ( B. ![]() Caprine brucellosis has been controlled in most industrialized countries however, this disease remains endemic in resource-limited settings, where small ruminants are the major livestock species and the main economical livelihood, such as the Mediterranean region, the Middle East, Central Asia, sub-Saharan Africa, and parts of Latin America. Approximately 90% of goats are located in the developing world, where they are considered one of the most important sources of protein for humans. Worldwide, there are approximately 1 billion goats, with an increase of the population by more than 20% in the last 10 years. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist.īrucella melitensis is the etiological agent of caprine brucellosis, an infectious zoonotic disease with significant economic impact on both the livestock industry and public health. (Grant # PE 1115052) (CAR) and the National Institutes of Health (NIH), International Research Scientist Development Award-IRSDA/ K01 (Grant # 1K01 TW009981-01) (AMAG). ![]() This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: This work was supported by the Agencia Nacional de Promoción Científica y Tecnológica de Argentina (Grant # PICT 2013-406) (CAR EM), I.N.T.A. PLoS Negl Trop Dis 11(8):Įditor: Mazin Barry, King Saud University College of Medicine, SAUDI ARABIAĬopyright: © 2017 Rossetti et al. Successful control leading to eradication of caprine brucellosis in the developing world will require a coordinated Global One Health approach involving active involvement of human and animal health efforts to enhance public health and improve livestock productivity.Ĭitation: Rossetti CA, Arenas-Gamboa AM, Maurizio E (2017) Caprine brucellosis: A historically neglected disease with significant impact on public health. In this review, we describe a historical evolution of the disease, highlight the current worldwide distribution, and estimate (by simple formula) the approximate costs of brucellosis outbreaks to meat- and milk-producing farms and the economic losses associated with the disease in humans. While the disease has been successfully managed in most industrialized countries, it remains a significant burden on goat and human health in the Mediterranean region, the Middle East, Central and Southeast Asia (including India and China), sub-Saharan Africa, and certain areas in Latin America, where approximately 3.5 billion people live at risk. melitensis for centuries but around 1905, the Greek physician Themistokles Zammit was able to build the epidemiological link between “Malta fever” and the consumption of goat milk. Historical observations indicate that goats have been the hosts of B. melitensis is also the most virulent Brucella species for humans, responsible for a severely debilitating and disabling illness that results in high morbidity with intermittent fever, chills, sweats, weakness, myalgia, abortion, osteoarticular complications, endocarditis, depression, anorexia, and low mortality. Middle- to late-term abortion, stillbirths, and the delivery of weak offspring are the characteristic clinical signs of the disease that is associated with an extensive negative impact in a flock’s productivity. If you're opposed to Electron or just have a machine that doesn't have a lot of RAM, Caprine probably isn't for you.Caprine brucellosis is a chronic infectious disease caused by the gram-negative cocci-bacillus Brucella melitensis. Caprine ran fine on my systems, but it did take up significantly more RAM than Facebook's first-party app when idle. Some will criticize Caprine for being Electron based, but I don't hold the hatred that many do for Electron. Caprine is free, easy to use, and works well. It's more than just a web wrapper and I think options are always a positive.Įven if you are more of a casual Facebook Messenger user, there's no reason not to give it a try. If you're on Facebook Messenger a lot, I recommend giving Caprine a try. But customizing Facebook Messenger might not be as important to many as customizing an app like Slack, which many people look at all day. These are excellent features and I'm always a fan of more options. Caprine offers a customizable interface with light and dark themes, the option to toggle elements of the interface on and off, keyboard shortcuts, and more.
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